It's never too late to quit

Smoking is the number one risk factor for lung disease in those born with Alpha-1. The European Lung Foundation and the European Respiratory Society describe the benefits of quitting smoking in two excellent diagrams. Remember no matter how late in life one quits there are benefits to be gained. Avoiding smoking at all costs is incredibly important for anyone with Alpha-1. This is because if you have Alpha-1 and are a smoker, you will develop severe early onset lung disease in the form of COPD or emphysema. 
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ERS ELF quitting smoking the benefits1

ERS ELF quitting smoking the benefits2