Latest News

Do you want to share your experience of participating in a clinical trial?

A new European project called EUPATI is trying to collect the real life experiences of patients who have participated in medicines development and clinical trials. People with Alpha-1 who have participated in clinical trials are encouraged to take part by the deadline of April 11th.

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Do you want to share your experience of participating in a clinical trial?

A new European project called EUPATI is trying to collect the real life experiences of patients who have participated in medicines development and clinical trials. People with Alpha-1 who have participated in clinical trials are encouraged to take part by the deadline of April 11th.

Read more...
 
Prestigious Award for the National Alpha-1 Antitrypsin Deficiency Screening Programme

The Alpha One Foundation has won a prestigious award for the National Alpha-1 Antitrypsin Deficiency Screening Programme at the Irish Healthcare Centre Awards held at the Royal Marine Hotel in DĂșn Laoghaire on March 7th. 

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New Irish study shows carriers of the Z Alpha-1 gene who smoke are at increased risk of COPD

Researchers from the Alpha One Foundation, the Royal College of Surgeons in Ireland and Harvard University have made a major breakthrough in identifying people who have an increased risk of developing COPD (chronic obstructive pulmonary disease) due to a combination of 1 copy of the Z Alpha-1 gene (MZ carriers) and exposure to cigarette smoke.

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Research Breakthrough in Understanding Alpha-1 by Irish Scientists
The Irish Times, the Irish Examiner, the RTE website, the Evening Herald and several other newspapers have this week (January 13th) reported a new discovery by scientists based at the Royal College of Surgeons of Ireland and Beaumont Hospital. 
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Irish Independent Interviews Alpha-1 Patient After Successful Double Lung Transplant

The Irish Independent published an interview with Alpha-1 patient Stephen Smith on the 2nd of January. After seven unsuccessful calls Stephen finally received a successful double lung transplant in the Mater Hospital, Dublin in November 2013. 

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What is Alpha-1 Antitrypsin?

Alpha-1 antitrypsin is an important protein produced by the liver, which is released into the bloodstream and travels to the lungs. Once inside the lungs it provides protection from the destructive effects of infections and harmful irritants, particularly tobacco smoke.

Alpha-1 Antitrypsin Deficiency

Alpha-1 antitrypsin deficiency (Alpha-1) is a genetic condition which, along with cystic fibrosis, is the commonest genetic lung disease in Ireland. It severely affects more than 2,000 people nationally, with another 10,000 individuals also at risk of lung and liver disease. It is the only proven genetic risk factor for COPD.

Welcome to the Alpha One Foundation

The Alpha One Foundation was established in 2001 to promote research into Alpha-1 Antitrypsin Deficiency (Alpha-1) and to improve the diagnosis, treatment, life expectancy and quality of life of people with this inherited condition.