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What is Alpha-1 Antitrypsin?
Alpha-1 Antitrypsin is an important protein produced by the liver, which is released into the bloodstream and travels to the lungs. Once inside the lungs it provides protection from the destructive effects of infections and harmful irritants, particularly tobacco smoke.
Alpha-1 Antitrypsin Deficiency
Alpha-1 antitrypsin deficiency (Alpha-1) is a genetic condition which, along with cystic fibrosis, is the commonest genetic lung disease in Ireland. It severely affects more than 2,000 people nationally, with another 10,000 individuals also at risk of lung and liver disease. It is the only proven genetic risk factor for COPD.
Welcome to Alpha One Foundation
The Alpha One Foundation was established in 2001 to promote research into Alpha-1 Antitrypsin Deficiency (Alpha-1) and to improve the diagnosis, treatment, life expectancy and quality of life of people with this inherited condition.