Not many people have heard of Alpha-1 and it was new to me until about nine years ago when my brother died.

Josephine McGuirk pictured with Beaumont Hospital CEO Liam Duffy at the launch of the smoke-free Beaumont Hospital campaign in 2012. 

Read Josephine's Story

Since I was first diagnosed with Alpha-1 Antitrypsin Deficiency in January 1990 my life has been a bit of a roller coaster.

Read Joe's Story